Disrupted Healthcare – Deals and Investments – 26 Transactions This Week

VC Deals (16 deals, $350M)

Cambridge Epigenetix, a UK-based developer of epigenetic tools, has raised $21 million in Series B funding. Google Ventures led the round, and was joined by Wellcome Trust, Sequoia Capital, New Science Ventures and Cambridge Enterprise

Spirox Inc., a Menlo Park, Calif.-based developer of minimally-invasive devices for patients with nasal obstruction, has raised $45 million in Series C funding.KKR led the round, and was joined by HealthQuest Capital and return backers Aisling Capital, Aperture Venture Partners and Venrock

Outpost Medicine, a biopharma startup focused on the development of new treatments of urologic and gynecologic diseases and disorders, has raised $41 million in first-round funding. Frazier Healthcare Partners led the round, and was joined by Adams Street Partners, Novo A/S, and Vivo Capital. Outpost was recently formed by Frazier Healthcare Partners and Takeda Pharmaceutical Co. (Tokyo: 4502), with Takeda granting Outpost an exclusive license for the global development and commercialization rights to OP-233 (formerly TAK-233), a clinical-stage product candidate being studied for the treatment of stress urinary incontinence

Arterys Inc., a San Francisco-based startup focused on “deep learning in medical imaging,” has raised over $12 million in Series A funding. Emergent Medical Partnersled the round, and was joined by GE Ventures, the Stanford-StartX Fund, Norwich Ventures, Asset Management Ventures, AME Cloud Ventures and Morado Ventures

Sight Sciences Inc., a Menlo Park, Calif.-based ophthalmic medical device startup, has raised $7 million in Series B funding. Hicks Equity Partners led the round, and was joined by return backers Scientific Health Development and Allegro Investment Fund

Prenetics, a Hong Kong-based developer of genetic testing solutions that aid in medicine prescriptions, has raised $10 million in Series A funding. Ping An Ventures led the round, and was joined by Venturra Capital, Capital Union Investments and return backers 500 Startups and Coent Venture #healthtechasia

10x Genomics, a Pleasanton, Calif.-based genomics sequencing company, has raised $55 million in Series C funding. Fidelity led the round, and was joined by Softbank, JS Capital Management and return backers Venrock, Foresite Capital and Paladin Capital

Gecko Biomedical, a Paris-based developer of polymers to support tissue healing, has raised €22.5 million in Series A2 funding. Sofinnova Partners led the round, and was joined by return backers Omnes Capital, CM-CIC Innovation and CapDecisif Management

Pieces Technologies, a Dallas-based health IT and data analytics startup that develops patient warning tools, has raised $21.6 million in Series A funding.Pacific Advantage Capital and Jump Capital co-led the round, and were joined by Children’s Health, the Order of Saint Francis Healthcare System and PCCI

BioAgilytix, a Durham, N.C.-based provider of contract bioanalytical testing services, has acquired IPM Biotech, a German bioanalytical contract research laboratory focused on immunogenicity. No financial terms were disclosed. BioAgilytix is a portfolio company of The Riverside Company

HealthTell, a five-year-old, San Ramon, Ca.-based diagnostics company that aims to commercialize panels for tests for autoimmune diseases like lupus, has raised $26 million in Series B funding led by Third Point Ventures

DiACardio, a seven-year-old, Beer Sheva, Israel-based software company that makes decision-support tools for cardiologists using echocardiography, has raised $1.95 million in a post seed financing round led by Shengjing Grou, with participation from CE Ventures, AltaIR, and earlier backers Agate-Mac Fund and Capital Point

ApniCure, a nine-year-old, Redwood City, Ca.-based startup whose medical device aims to treat sleep apnea, has raised $15.8 million toward a $17.4 million financing, according to an SEC filing first flagged by VentureWire. The company previously raised capital from Capricorn Investment GroupKleiner Perkins Caufield & Byers and U.S. Venture Partners

Atlantic Healthcare, a nine-year-old, U.K.-based specialty pharmaceutical company focused on gastrointestinal disorders, has raised $24 million in funding from LDC, Fullbrook Thorpe Investments, the founders of Salix Pharmaceuticals, and earlier investors

eGym, a five-year-old, Munich, Germany-based startup that offers cloud-connected gym equipment and supporting cloud software and apps for fitness training, has raised $45 million in Series C funding led by HPE Growth Capital, with participation from earlier backers, including Highland Europe

India based home healthcare startup Pramati Healthcare Pvt Ltd has raised $200,000 in pre-Series A funding from three strategic investors #healthtechasia

PE Deals (5 deals)

CVC Capital Partners has agreed to acquire Italian generic drugmaker Doc Generici from Charterhouse. No financial terms were disclosed, but an earlierReuters report put the asking price at between €650 million and €700 million

Spring & Sprout Dental Holdings, a dental practice acquisition platform sponsored by Huron Capital Partners, has acquired Dan German Orthodontics(Beaverton, Ohio). No financial terms were disclosed

Bain Capital has invested $150 million for a control stake in Asia Pacific Medical Group, a China-focused hospital operator

ExactCare Pharmacy, a Cleveland-based pharmacy focused on improving medication adherence for patients with chronic conditions and on multiple medications, has secured an undisclosed amount of private equity funding fromNautic Partners

Halex Istar, a Brazil-based maker of pharmaceutical parenteral solutions, has secured an undisclosed amount of private equity funding from H.I.G. Capital. Proceeds will be used to acquire local rival Isofarma

IPO Deals (2 deals)

Hutchison China MediTech, a China-focused oncology pharma company backed by CK Hutchinson (Hong Kong: 1), raised $101 million in its IPO. The company priced 7.5 million American depository shares at $13.50 per share. This compares to plans to offer 6.1 million shares at $16.33, which was the issuer’s previous trading price on London’s AIM market. It will trade on the Nasdaq under ticker symbol HCM, while BofA Merrill Lynch and Deutsche Bank served as lead underwriters

Senseonics, a Germantown, Md.-based provider of glucose monitoring devices, raised $45 million in its IPO. The company priced 15.8 million shares at $2.85 per share, compared to plans to offer 18.2 million shares at between $3.10 and $3.50 per share. The company’s stock had been traded on the OTCQB under ticker symbol SENH, and it will relist on the NYSE MKT under symbol SENS. Leerink Partners and Canaccord Genuity served as lead underwriters. Senseonics had raised VC funding from such firms as New Enterprise Associates (33% pre-IPO stake), Delphi Ventures (13.4%), HealthCare Ventures (7.4%), Roche Finance (10.5%) and Energy Capital (9.9%)

Other Deals (3 deals)

Magellan Health (Nasdaq: MGLN) has acquired The Management Group Inc., a Madison Wis.-based provider of Medicaid home and community-based waiver quality assurance and improvement services. No financial terms were disclosed

Sanofi has agreed to a partnership with Menlo Park, Calif.-based DiCE Molecules that could be valued at upwards of $2.3 billion. The deal, which focuses on finding new oral medicines to replace injections for certain diseases, also includes Sanofi acquiring an equity stake in DiCE

Primary Health Care (ASX: PRY) saw its shares climb more than 5% after it confirmed that Hong Kong-based Haitong Group had amassed a 5.78% equity stake. It is unclear if the purchase is designed to precipitate a takeover offer for the Australian medical services company, which now has a market cap of around A$1.9 billion

Sources: Term Sheet, Financial Times, StrictlyVC, TechinAsia, CrunchBase, TechCrunch, Bloomberg, MobiHealthNews

The Propell Group

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